1 day ago Be among the first 25 applicants Get AI-powered advice on this job and more exclusive features. Aerial Talent provided pay range This range is provided by Aerial Talent. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range $170,000.00/yr - $250,000.00/yr Direct message the job poster from Aerial Talent Well-funded biotech in SSF seeks a Computational Chemistry Director or Senior Director with experience in CADD- and structure-based design for lead optimization of small molecules to advance the pipeline of innovative therapeutics toward the clinic. This position requires regular onsite presence in South San Francisco, CA. Highlights Reports to SVP, Discovery Potential to have one or more direct reports Two lead targets: CNS oncology + neurodegeneration Financial runway forecasted through Spring 2027 Responsibilities Provide strategic leadership and hands‑on execution of our CADD efforts Collaborate closely with chemists and biologists on virtual screening, hit identification and structure‑based design Guide the optimization of drug candidates that induce protein degradation Use machine‑learning (ML) to build in silico models to predict DMPK properties Perform and automate high‑throughput molecular dynamics simulations to predict protein function and protein‑ligand binding Utilize established tools and design new methods/tools Scientific programming as needed Required Qualifications PhD in Computational Chemistry or related discipline 10+ years of relevant experience in drug discovery #J-18808-Ljbffr Aerial Talent
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